Induced Systemic Resistance 
The ability of a plant to respond to attacks and stresses from pests and diseases can be enhanced with the application of a biological or chemical inducer which helps protect, by creating a protective barrier in, areas of a plant that haven't been the primary area of attack. This response process is activated once a plant has become infected or stressed by a pathogen. Materials with beneficial microbes can be applied to plants to aid their resilience to attacks and stress from pests and disease. A build-up of beneficial microbes within the rhizosphere would occur over time thereby creating an environment in which plants can enhance their defensive capability in advance of any potential threat. Coating seeds with an ISR compound may also help to reduce damage from diseases and nematodes, for example, at germination and initial establishment stage. (Main source: Romera Francisco J., GarcÃa MarÃa J., Lucena Carlos, MartÃnez-Medina Ainhoa, Aparicio Miguel A., Ramos José, Alcántara Esteban, Angulo Macarena, Pérez-Vicente Rafael (2019), 'Induced Systemic Resistance (ISR) and Fe Deficiency Responses in Dicot Plants', Frontiers in Plant Science, Vol. 10, https://www.frontiersin.org/article/10.3389/fpls)